发明名称 |
MODULATION OF THE INTERACTION BETWEEN EVH1 DOMAINS |
摘要 |
The invention relates to methods for the identification of chemical compounds which can modulate the interaction between VASP and zyxin. VASP or a VASP derivative and zyxin or a zyxin derivative, which interact with each other, are brought into contact with a chemical compound under investigation. The influence on the interaction can be determined by means of antibodies for VASP or a VASP derivative and/or zyxin or a zyxin derivative, or by means of fluorescent markings on VASP or a VASP derivative and zyxin or a zyxin derivative. |
申请公布号 |
WO0242777(A3) |
申请公布日期 |
2004.01.15 |
申请号 |
WO2001EP13592 |
申请日期 |
2001.11.22 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH;VASOPHARM BIOTECH GMBH |
发明人 |
JORDAN, BIRGIT;DRUECKES, PETER;JARCHAU, THOMAS;WALTER, ULRICH |
分类号 |
G01N33/566;A61K38/00;A61K45/00;A61P9/00;A61P29/00;A61P35/00;A61P43/00;C07K14/47;C07K16/18;C12N5/10;C12P21/08;G01N33/15;G01N33/50;G01N33/53;G01N33/68 |
主分类号 |
G01N33/566 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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