| 发明名称 |
Recombinant Streptomyces hygroscopicus host cells that produce 17-desmethylrapamycin |
| 摘要 |
Recombinant host cells that produce rapamycin analogues are constructed by deleting or modifying rapamycin biosynthetic gene cluster genes and are useful in the production of compounds used as antifungals, anticancers, immunosuppressants, and neurotrophins.
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| 申请公布号 |
US6670168(B1) |
申请公布日期 |
2003.12.30 |
| 申请号 |
US20000702029 |
申请日期 |
2000.10.30 |
| 申请人 |
KOSAN BIOSCIENCE, INC. |
发明人 |
KATZ LEONARD;LIU LU;CHUNG LOLETA M. |
| 分类号 |
C07D498/18;C12N1/21;C12N9/10;C12N15/52;C12P17/18;(IPC1-7):C12N1/20 |
主分类号 |
C07D498/18 |
| 代理机构 |
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