发明名称 HUMAN CYSTATHIONINE β-SYNTHASE VARIANTS AND METHODS OF PRODU CTION THEREOF
摘要 <p>Human cystathionine β -synthase variants are disclosed, as well as a method to produce recombinant human cystathionine β -synthase and variants thereof. More particularly, the role of both the N-terminal and C-terminal regions of human CBS has been studied, and a variety of truncation mutants and modified CBS homologues are described. In addition, a method to express and purify recombinant human cystathionine β -synthase (CBS) and variants thereof which have only one or two additional amino acid residues at the N-terminus are described.</p>
申请公布号 WO2003106971(P1) 申请公布日期 2003.12.24
申请号 US2003019156 申请日期 2003.06.17
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