| 摘要 |
FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to compounds representing azacyclic compounds azaadamantanes, azanoradamantanes and azahomoadamantanes of the general formula (I): including geometric isomers, enantiomers, diastereomers, racemates and pharmaceutically acceptable salts wherein Q is ; X means sulfur atom; R means OR3 or -SR3 or halogen atom wherein R3 is linear or branched or cyclic C1-C10-alkyl or their combinations; Y and Z mean nitrogen atom; n and m = 0, 1, 2, 3 or 4 independently; R1 and R2 mean hydrogen or halogen atom independently. New compounds of the formula (I) and pharmaceutical compositions based on thereof are useful for pain treatment. EFFECT: valuable medicinal properties of compounds. 14 cl, 3 tbl, 25 ex |
