The present invention relates to genetically modified microorganisms, in particular coryneform bacteria and Escherichia coli, in which the phosphorylation state of proteins or polypeptides has been changed such that the bacteria produce a larger amount of a desired fine chemical or a metabolite than the wild type, and to a method for the production of fine chemicals or metabolites.
申请公布号
WO03023016(A3)
申请公布日期
2003.11.20
申请号
WO2002EP10174
申请日期
2002.09.11
申请人
DEGUSSA AG;BATHE, BRIGITTE;BUSKER, EBERHARD;KRUSE, DANIELA;RIEPING, MECHTHILD;VENZAGO, CORNEL;FARWICK, MIKE;HERMANN, THOMAS
发明人
BATHE, BRIGITTE;BUSKER, EBERHARD;KRUSE, DANIELA;RIEPING, MECHTHILD;VENZAGO, CORNEL;FARWICK, MIKE;HERMANN, THOMAS