| 发明名称 |
Method of treating migraine headaches with a highly selective norepinephrine reuptake inhibitor |
| 摘要 |
Methods for treating humans suffering from, migraine headaches by inhibiting reuptake of norepinephrine are disclosed. The methods comprise a compound having a pharmacological selectivity of serotonin (Ki)/norepinephrine (Ki) of at least about 5000. Examples of such compounds include reboxetine, and more preferably optically pure (S,S) enantiomer of reboxetine.
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| 申请公布号 |
US6642235(B2) |
申请公布日期 |
2003.11.04 |
| 申请号 |
US20020099334 |
申请日期 |
2002.01.04 |
| 申请人 |
PHARMACIA & UPJOHN COMPANY |
发明人 |
WONG ERIK H. F.;AHMED SAEEDUDDIN;MARSHALL ROBERT C.;MCARTHUR ROBERT;TAYLOR DUNCAN P. |
| 分类号 |
A61K45/00;A61K31/00;A61K31/5375;A61P1/14;A61P3/04;A61P11/00;A61P13/10;A61P25/00;A61P25/02;A61P25/06;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P39/02;A61P43/00;(IPC1-7):A61K31/535 |
主分类号 |
A61K45/00 |
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