| 发明名称 |
HUMAN ANTI-OPGL NEUTRALIZING ANTIBODIES AS SELECTIVE OPGL PATHWAY INHIBITORS |
| 摘要 |
Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a samp le using antibodies to OPGL are further provided.
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| 申请公布号 |
CA2481074(A1) |
申请公布日期 |
2003.10.23 |
| 申请号 |
CA20032481074 |
申请日期 |
2003.04.07 |
| 申请人 |
AMGEN INC. |
发明人 |
MARTIN, FRANCIS HALL;HUANG, HAICHUN;ELLIOTT, ROBIN L.;SULLIVAN, JOHN K.;BOYLE, WILLIAM J.;MEDLOCK, EUGENE |
| 分类号 |
C12N15/09;A61K39/395;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P43/00;C07K16/24;C07K16/28;(IPC1-7):C07K16/24;G01N33/53 |
主分类号 |
C12N15/09 |
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