| 发明名称 |
PROCESS FOR THE SYNTHESIS OF (R)-1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-OL AND ESTERS THEREOF BY DYNAMIC KINETIC RESOLUTION |
| 摘要 |
The present invention is concerned with novel processes for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-ol and esters thereof via dynamic kinetic resolution. These compounds are useful as intermediates in the synthesis of compounds which possess pharmacological activity. |
| 申请公布号 |
WO03043575(A3) |
申请公布日期 |
2003.10.16 |
| 申请号 |
WO2002US36969 |
申请日期 |
2002.11.15 |
| 申请人 |
MERCK & CO., INC.;BROXTERMAN, QUIRINUS BERNARDUS;VERZIJL, GERARDUS KAREL MARIA |
发明人 |
BROXTERMAN, QUIRINUS BERNARDUS;VERZIJL, GERARDUS KAREL MARIA |
| 分类号 |
C07C17/12;C07C29/09;C07C29/143;C07C29/56;C07C45/00;C07C69/007;C07C69/63;C12P7/62;C12P41/00 |
主分类号 |
C07C17/12 |
| 代理机构 |
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