发明名称 |
Snail, new tumoral progression marker and target protein of new antitumoral compounds |
摘要 |
The Snail transcription factor has been identified as a repressor of the expression of E-cadherin. The expression of Snail induces invasive and metastatic capacity in tumour cells. This invention presents: a new target protein, Snail, for the identification of new antitumoral compounds and a new diagnostic tumour -marker, indicative of tissue invasion and metastatic capacity. |
申请公布号 |
AU5408300(A) |
申请公布日期 |
2001.01.22 |
申请号 |
AU20000054083 |
申请日期 |
2000.06.27 |
申请人 |
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS;UNIVERSIDAD AUTONOMA DE MADRID |
发明人 |
AMPARO CANO GARCIA;MARIA ANGELA NIETO TOLEDANO;MARIA ISABEL RODRIGO CASTRO;ANNAMARIA LOCASCIO;MARTA GARCIA DEL BARRIO;MARIA JOSE BLANCO FERNANDEZ DE VALDERRAMA;FRANCISCO PORTILLO PEREZ;MIRNA ALICIA PEREZ MORENO |
分类号 |
A61K38/00;A61K48/00;C07K14/47;C12Q1/68;G01N33/574 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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