发明名称 METHODS OF ENHANCING IMMUNE INDUCTION INVOLVING MDA-7
摘要 The present invention relates to compositions and methods for the enhancing or inducing an immune response against an immunogenic molecule by indirectly activating PKR. More specifically, immunotherapy is improved by co-administering a MDA-7 polypeptide with an immunogenic molecule against which an immune response is desired. Such immunotherapies include cancer vaccines, and compositions thereof are described.
申请公布号 WO03075952(A1) 申请公布日期 2003.09.18
申请号 WO2003US06489 申请日期 2003.03.03
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;INTROGEN THERAPEUTICS, INC.;CHADA, SUNIL;PATAER, ABUJIANG;RAMESH, RAJAGOPAL;MHASHILKAR, ABNER;ROTH, JACK;SWISHER, STEVE 发明人 CHADA, SUNIL;PATAER, ABUJIANG;RAMESH, RAJAGOPAL;MHASHILKAR, ABNER;ROTH, JACK;SWISHER, STEVE
分类号 C12N15/09;A61K31/7088;A61K38/00;A61K39/00;A61K39/02;A61K39/12;A61K39/20;A61K39/21;A61K39/235;A61K39/245;A61K48/00;A61P35/00;A61P37/02;C07K14/47;C07K14/54;(IPC1-7):A61K39/00;C07H21/04;C07K5/00 主分类号 C12N15/09
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