发明名称 Piperazinylcarbonyl quinoline and piperazinylcarbonyl isoquinoline derivative, process of its preparation, its use and pharmaceutical preparation in which the derivative is comprised
摘要 <p>Compound of the formula (I) in which R<SUP>1</SUP>, R<SUP>2 </SUP>and alk are as defined in Claim 1, are potent 5-HT<SUB>2A </SUB>antagonist and are suitable for the treatment of psychoses, schizophrenia, depression, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease, Hutington's disease, eating disorders, such as bulimia, anorexia nervosa, premenstrual syndrome and/or for positively influencing obsessive-compulsive disorder (OCD).</p>
申请公布号 CZ20031861(A3) 申请公布日期 2003.09.17
申请号 CZ20030001861 申请日期 2001.12.24
申请人 MERCK PATENT GMBH 发明人 BOTTCHER HENNING;BARTOSZYK GERD;HARTING JURGEN;VAN AMSTERDAM CHRISTOPH;SEYFRIED CHRISTOPH
分类号 C07D403/06;A61K31/495;A61K31/496;A61K45/00;A61P21/00;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P25/30;A61P29/00;A61P43/00;C07D215/48;C07D217/26;(IPC1-7):C07D403/12;A61K31/470;A61K31/472 主分类号 C07D403/06
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