| 摘要 |
The present invention provides a method of making particles, e.g., nanoparticles that are stable in a physiological environment for at least a day. The nanoparticles comprise polyanionic polymers and polycations in a complex useful for drug delivery. The method comprises the step of capturing droplets comprising the polyanionic polymers in a solution comprising the polycations; or, alternatively, capturing droplets comprising the polycations in a solution comprising the polyanionic polymers. Also provided are methods of use for the particles.
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