发明名称 |
Cyclic peptides that bind to urokinase-type plasminogen activator receptor |
摘要 |
Cyclic peptide compounds having 11 amino acids joined by a linking unit L, such that the linear dimension between the Calpha carbon of the first amino acid and the Calpha carbon of eleventh amino acid is between about 4 and 12 Ångstrom units; are useful for inhibiting the binding of uPA to the uPAR receptor.: Methods for using the cyclic peptide compounds, and compositions containing them, for inhibiting the growth or metastasis of cancerous tumors are also disclosed.
|
申请公布号 |
US2003166514(A1) |
申请公布日期 |
2003.09.04 |
申请号 |
US20030349543 |
申请日期 |
2003.01.22 |
申请人 |
JONES TERENCE R.;HANEY DAVID N.;VARGA JANOS |
发明人 |
JONES TERENCE R.;HANEY DAVID N.;VARGA JANOS |
分类号 |
A61K38/00;C07K7/54;C12N9/72;(IPC1-7):A61K38/12;C07K7/64 |
主分类号 |
A61K38/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|