| 发明名称 |
ANTIBODY VARIANTS WITH FASTER ANTIGEN ASSOCIATION RATES |
| 摘要 |
Antibody variants with faster antigen association rates are disclosed. The antibody variants have one or more amino acid alteration(s) in or adjacent to at least one hypervariable region thereof which increase charge complementarity between the antibody variant and an antigen to which it binds.
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| 申请公布号 |
CA2472922(A1) |
申请公布日期 |
2003.08.21 |
| 申请号 |
CA20032472922 |
申请日期 |
2003.02.11 |
| 申请人 |
GENENTECH, INC. |
发明人 |
MARVIN, JONATHAN S.;LOWMAN, HENRY B. |
| 分类号 |
C07K16/00;C07K16/24;C07K16/28;C07K16/32;(IPC1-7):C12N15/13;C12P21/02;C12N15/09;C07K16/22;A61K39/395;G01N33/557 |
主分类号 |
C07K16/00 |
| 代理机构 |
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