| 发明名称 |
MURINE MONOCLONAL ANTIBODY (5c8) RECOGNIZES A HUMAN GLYCOPROTEIN ON THE SURFACE OF T-LYMPHOCYTES |
| 摘要 |
<p>This invention provides a monoclonal antibody capable of binding to a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention also provides an isolated protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC Accession No. HB 10916. This invention further provides an isolated nucleic acid molecule encoding a protein which is specifically recognized by monoclonal antibody 5c8 produced by the hybridoma having ATCC No. HB 10916. This invention also provides a human CD4<-> T cell leukemia cell line designated D1.1 having ATCC Accession No. CRL 10915 capable of constitutively providing cotnact-dependent helper function to B cells.</p> |
| 申请公布号 |
EP0614374(B1) |
申请公布日期 |
2003.08.13 |
| 申请号 |
EP19920925316 |
申请日期 |
1992.11.16 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
LEDERMAN, SETH;CHESS, LEONARD;YELLIN, MICHAEL, J. |
| 分类号 |
G01N33/50;A61K35/76;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61K47/48;A61K48/00;A61K49/00;A61K51/10;A61P3/10;A61P5/14;A61P7/04;A61P7/06;A61P17/06;A61P19/02;A61P21/04;A61P29/00;A61P31/14;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K14/47;C07K14/705;C07K14/725;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/09;C12N5/10;C12N15/02;C12N15/09;C12N15/12;C12N15/13;C12P21/02;C12P21/08;C12Q1/02;C12R1/91;G01N33/15;G01N33/53;G01N33/566;G01N33/574;G01N33/577;(IPC1-7):C12N15/12;C12N5/08;C07K16/18;C07K16/46 |
主分类号 |
G01N33/50 |
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