COMBINATION OF 2-METHOXYESTRADIOL AND AN AGENT THAT INCREASES INTRACELLULAR SUPEROXIDE ANION
摘要
The instant invention discloses methods and compositions for the treatment of cancer. The invention relates methods and compositions for specifically targeting free radical accumulation as a means of preferentially eliminating neoplastic cells. The combination of an SOD inhibitor (2-methoxyestrdiol) with free radical-producing agents results in a means of eliminating tumor cells through the accumulation of intracellular superoxide anion.
申请公布号
WO0203979(A3)
申请公布日期
2003.07.24
申请号
WO2001US22332
申请日期
2001.07.11
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;HUANG, PENG;PLUNKETT, WILLIAM, K.;FENG, LI