摘要 |
There are disclosed beta-sheet mimetics and methods relating to the same for imparting or stabilizing the beta-sheet structure of a peptide, protein or molecule. In one aspect, the beta-sheet mimetics are covalently attached at the end or within the length of the peptide or protein. The beta-sheet mimetics have utility as protease inhibitors generally, including activity as serine protease inhibitors such as thrombin, elastase and Factor X.
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