发明名称 STAUROSPORINE DERIVATIVES AS INHIBITORS OF FLT3 RECEPTOR TYROSINE KINASE ACTIVITY
摘要 The present invention relates to the use of staurosporines derivatives for the preparation of a drug for the treatment of diseases involving deregulated FLT3 receptor tyrosine kinase activity, especially for the curative and/or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving deregulated FLT3 receptor tyrosine kinase activity.
申请公布号 WO03037347(A1) 申请公布日期 2003.05.08
申请号 WO2002EP12076 申请日期 2002.10.29
申请人 NOVARTIS AG;NOVARTIS PHARMA GMBH;DANA-FARBER CANCER INSTITUTE INC.;GRIFFIN, JAMES, DOUGLAS;MANLEY, PAUL, WILLIAM 发明人 GRIFFIN, JAMES, DOUGLAS;MANLEY, PAUL, WILLIAM
分类号 C07D498/22;A61K31/155;A61K31/407;A61K31/535;A61K31/55;A61K31/553;A61P19/08;A61P35/02;A61P43/00;(IPC1-7):A61K31/535;C07D487/04;C07D487/14;C07D519/00 主分类号 C07D498/22
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