发明名称 |
A SYNTHETIC CHIMERIC FUSION PROTEIN WITH IMMUNO-THERAPEUTIC USES |
摘要 |
The present invention relates to an immuno-therapy conjugate which comprises A- c-B wherein: A and B are different and are compoun ds selected from the group consisting of cytokines, chemokines, interferons, their respective receptors or a functional fragment thereof; andc is a linker consisting of a bond or an amino acid sequence containing from 1 to 100 residues. The present invention also relates to a vaccine adjuvant comprising the immuno-therapy conjugate of the present invention. The present invention further relates to a method of reducing tumor growth, for inhibiting a viral infection and for improving immune response in a patient.
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申请公布号 |
CA2471532(A1) |
申请公布日期 |
2003.05.01 |
申请号 |
CA20022471532 |
申请日期 |
2002.10.23 |
申请人 |
CENTRE FOR TRANSLATIONAL RESEARCH IN CANCER |
发明人 |
STAGG, JOHN;GALIPEAU, JACQUES |
分类号 |
A61K38/00;A61K39/00;A61K39/39;A61K48/00;A61P35/00;C07K14/535;C07K14/55;(IPC1-7):C12N15/62;C07K19/00;A61P31/00;A61K38/19;C12N15/19;C12N15/26;C12N15/27;C07K14/52;A61K31/708;C07K14/715 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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