发明名称 A SYNTHETIC CHIMERIC FUSION PROTEIN WITH IMMUNO-THERAPEUTIC USES
摘要 The present invention relates to an immuno-therapy conjugate which comprises A- c-B wherein: A and B are different and are compoun ds selected from the group consisting of cytokines, chemokines, interferons, their respective receptors or a functional fragment thereof; andc is a linker consisting of a bond or an amino acid sequence containing from 1 to 100 residues. The present invention also relates to a vaccine adjuvant comprising the immuno-therapy conjugate of the present invention. The present invention further relates to a method of reducing tumor growth, for inhibiting a viral infection and for improving immune response in a patient.
申请公布号 CA2471532(A1) 申请公布日期 2003.05.01
申请号 CA20022471532 申请日期 2002.10.23
申请人 CENTRE FOR TRANSLATIONAL RESEARCH IN CANCER 发明人 STAGG, JOHN;GALIPEAU, JACQUES
分类号 A61K38/00;A61K39/00;A61K39/39;A61K48/00;A61P35/00;C07K14/535;C07K14/55;(IPC1-7):C12N15/62;C07K19/00;A61P31/00;A61K38/19;C12N15/19;C12N15/26;C12N15/27;C07K14/52;A61K31/708;C07K14/715 主分类号 A61K38/00
代理机构 代理人
主权项
地址