发明名称 |
Yeast-based process for production of l-pac |
摘要 |
The invention provides a method of synthesis of a substituted or unsubstituted carbinol compound, comprising the steps of subjecting the corresponding substituted or unsubstituted aromatic aldehyde to acyloin condensation mediated by yeast in the presence of either (a) a supercritical fluid or (b) a liquefied gas, and recovering the carbinol compound. Preferably the yeast is Saccharomyces cerevisiae. In a particularly preferred embodiment the aromatic aldehyde is benzaldehyde and the carbinol is pheny-lacetylcarbinol, according to the reaction (1): in which the benzaldehyde, the pyruvic acid, or both may optionally be substituted.
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申请公布号 |
US2003077769(A1) |
申请公布日期 |
2003.04.24 |
申请号 |
US20020149821 |
申请日期 |
2002.09.18 |
申请人 |
SMALLRIDGE ANDREW JOHN;TREWHELLA MAURICE ARTHUR;WILKINSON KYLIE ANNE |
发明人 |
SMALLRIDGE ANDREW JOHN;TREWHELLA MAURICE ARTHUR;WILKINSON KYLIE ANNE |
分类号 |
C12P7/26;(IPC1-7):C12P7/42;C12N1/18;C12P7/22 |
主分类号 |
C12P7/26 |
代理机构 |
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代理人 |
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地址 |
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