METHODS OF TREATING BONE CANCER AND THE PAIN ASSOCIATED THEREWITH USING ENDOTHELIN ANTAGONISTS

摘要

The instant invention is directed to methods for the inhibition of bone metastases, methods for the prevention of growth of new metastases, methods for the inhibition of bone turnover, and methods for the prevention of bone loss in patients, including cancer patients, using an endothelin ET-A receptor antagonist.