发明名称 |
PROCESS FOR PREPARING ALKANESULFONYL PYRIDINES |
摘要 |
A process for preparing alkanesulfonyl pyridines of the formula 1: (see formula I) is disclosed, wherein R1 is unsubstituted (C1-C6)alkyl. The compounds of formula 1 are useful in the preparation of pyridyl-substituted pyrazoles used in the treatment and alleviation of inflammation and other inflammation associated disorders. The process includes (a) reacting a compound of the formula: (see formula II) with a Grignard reagent, and (b) reacting the product of step (a) with an alkyl sulfonylating agent.
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申请公布号 |
CA2405328(A1) |
申请公布日期 |
2003.03.28 |
申请号 |
CA20022405328 |
申请日期 |
2002.09.26 |
申请人 |
PFIZER PRODUCTS INC., |
发明人 |
NOWAKOWSKI, JOLANTA;HAAG, DIETER CHRISTIAN |
分类号 |
C07D213/70;C07D213/71;C07D213/72;C07D213/73;C07D213/77;C07D401/04;(IPC1-7):C07D213/77 |
主分类号 |
C07D213/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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