| 摘要 |
<p>The invention relates to technical tools that are used to identify and select subspecies of pre-T lymphocytes using the pre-T cell receptor (pTα). Moreover, said invention relates to methods of regulating the expression and function of said receptor during the development of human T lymphocytes. In one particular embodiment, the invention relates to monoclonal antibody K5G3 which recognises the pTαa isoform in a specific manner, thereby enabling the expression of the pTα chain on the cellular surface to be analysed for the first time.</p> |
