发明名称 |
QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS |
摘要 |
The invention concerns quinoline derivatives of Formula (I) wherein each of Z, m, R<1>, n and R<3> have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.
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申请公布号 |
WO03008409(A1) |
申请公布日期 |
2003.01.30 |
申请号 |
WO2002GB03177 |
申请日期 |
2002.07.10 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;HENNEQUIN, LAURENT, FRANCOIS, ANDRE |
发明人 |
HENNEQUIN, LAURENT, FRANCOIS, ANDRE |
分类号 |
A61K31/4709;A61K31/496;A61K31/5377;A61K31/541;A61P1/16;A61P3/10;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/06;A61P19/08;A61P27/02;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07D401/14;C07D403/12;C07D403/14;C07D405/12;C07D405/14;C07D417/14;(IPC1-7):C07D403/12;A61K31/470 |
主分类号 |
A61K31/4709 |
代理机构 |
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代理人 |
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地址 |
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