发明名称 COMPOSITION AND METHOD FOR REDUCING ADVERSE INTERACTIONS BETWEEN PHENOTHIAZINE DERIVATIVES AND PLASMA USING CYCLODEXTRINS
摘要 Compositions and methods are provided for reducing adverse reactions as a result of parenteral administration of certain phenothiazine derivatives such as promethazine hydrochloride. The active compound may be admixed with an effective amount of one or more cyclodextrin derivatives, and if desired, one or more non-ionic surfactants such as the partial esters of sorbitol and the polyoxyethylene oxides of long chain fatty acids such as the polysorbates.
申请公布号 WO03002153(A1) 申请公布日期 2003.01.09
申请号 WO2002US20339 申请日期 2002.06.26
申请人 WYETH 发明人 YU, JIANWEI
分类号 A61K9/00;A61K31/5415;A61K47/26;A61K47/40;(IPC1-7):A61K47/40;A61K47/48;A61K31/541 主分类号 A61K9/00
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