NUCLEIC ACID PARTICIPATING IN THE FORMATION OF PRESENILIN−2−GENE EXON 5−DEFECTIVE SPLICING VARIANT
摘要
Means of treating and/or preventing diseases caused by a splicing variant, neurodegenerative diseases typified by Alzheimer’s disease and so on. A nucleic acid seemingly participating in the formation of a presenilin−2 exon 5−deficient splicing variant; an inhibitor inhibiting the binding between a protein and a nucleic acid causing the splicing variant; and a method of screening the inhibitor.
申请公布号
WO03002742(A1)
申请公布日期
2003.01.09
申请号
WO2002JP06462
申请日期
2002.06.27
申请人
JAPAN SCIENCE AND TECHNOLOGY CORPORATION;TAISHO PHARMACEUTICAL CO., LTD.;TOHYAMA, MASAYA;KATAYAMA, TAIICHI;MANABE, TAKAYUKI;IMAIZUMI, KAZUNORI;IKEDA, YOKO