RADIOPHARMACEUTICAL FORMULATIONS, THEIR METHOD OF ADMINISTRATION AND PROCESS OF PREPARATION

摘要

Radiopharmaceutical formulations for complexes comprising at least one radionuclide complexed with a ligand, or its physiologically-acceptable salts thereof, especially 153samarium-ethylenediaminetetramethylene- phosphonic acid, which optionally contains a divalent metal ion, e.g. calcium, and is frozen, thawed, and then administered by injection. Alternatively, the radiopharmaceutical formulations must contain the divalent metal and are frozen only if the time before administration is sufficiently long to cause concern for radiolysis of the ligand.