| 摘要 |
FIELD: stomatology. SUBSTANCE: two-side adhesive film contains one or more water-soluble polymers, plasticizer, if necessary partially water-soluble polymer, nonionic surfactants, and drugs. Film is manufactured by dissolving polymer and plasticizer in deionized water at 40-45 C or, if necessary at 80-85 C, after which cooled and filtered. If necessary, filtrate is supplemented by partially water-soluble polymer, stirred at 40-45 C and filtered. Resulting filtrate is dried in uniform layer on a surface at temperature no higher than 25 C in inert gas atmosphere until 5-10% water content in film is attained. EFFECT: eliminated damaging effects on contact with mucous tissues, denaturation of drugs, and allergic effects. 9 cl, 17 ex
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