Combination of a PTPase inhibitor and a thiazolidinedione agent

摘要

This invention provides methods of using a pharmacological combination of one or more PTPase inhibiting agents and one or more thiazolidinedione agents, including pioglitizone or rosiglitazone, for treatment in a mammal of Syndrome X or type II diabetes or metabolic disorders mediated by insulin resistance or hyperglycemia. Further included in this invention is a method of modulating blood glucose levels in a mammal utilizing the combination of one or more PTPase inhibiting agents and one or more thiazolidinedione agents.