NUCLEIC ACID CONSTRUCTS AND CELLS, AND METHODS UTILIZING SAME FOR MODIFYING THE ELECTROPHYSIOLOGICAL FUNCTION OF EXCITABLE TISSUES
摘要
A method of modifying the electrophysiological function of an excitable tissue region of an individual is provided. The method includes the step of implanting cells into the excitable tissue region. Each implanted cell is (a) capable of forming gap junctions with at least one cell of the excitable tissue region; and (b) capable of forming a functional ion channel or transporter, wherein the functional ion channel or transporter is capable of modifying the electrophysiological function of the excitable tissue region.
申请公布号
WO0233111(A3)
申请公布日期
2002.12.19
申请号
WO2001IL00833
申请日期
2001.09.05
申请人
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.;FELD, YAIR;GEPSTEIN, LIOR;MAROM, SHIMON;FRANK, MEIRA
发明人
FELD, YAIR;GEPSTEIN, LIOR;MAROM, SHIMON;FRANK, MEIRA