发明名称 |
N-(aryl/heteroaryl) amino acid derivatives, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds |
摘要 |
Disclosed are compounds which inhibit beta-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
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申请公布号 |
US6495693(B2) |
申请公布日期 |
2002.12.17 |
申请号 |
US19990280966 |
申请日期 |
1999.03.30 |
申请人 |
ATHENA NEUROSCIENCES, INC.;ELI LILLY & COMPANY |
发明人 |
AUDIA JAMES E.;FOLMER BEVERLY K.;JOHN VARGHESE;LATIMER LEE H.;NISSEN JEFFREY S.;PORTER WARREN J.;THORSETT EUGENE D.;WU JING |
分类号 |
A61K31/00;A61K31/198;A61K31/223;C07C237/08;C07C237/10;C07C237/12;C07C271/22;C07D209/20;C07D215/38;C07D233/54;C07D233/61;C07D277/62;C07D277/82;(IPC1-7):C07D277/82;C07D233/30;C07C229/72 |
主分类号 |
A61K31/00 |
代理机构 |
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地址 |
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