MACROLIDE COMPOUNDS, ANTIFUNGAL AGENTS USING THE SAME, MACROLIDE COMPOUND-PRODUCING BACTERIUM BELONGING TO THE GENUS SORANGIUM AND PROCESS FOR PRODUCING MACROLIDE COMPOUNDS USING THE SAME

摘要

Macrolide compounds having the following chemical structure, which are obtained by culturing Sorangium cellulosum, have an antifungal activity over various fungi such as those belonging to the genera Phytophthera, Absidia, Rhizopus and Aspergillus, show a low cytotoxicity on animal and plant cells and can be easily mass-produced industrially. (1) YA2-M :R=CH3 (2) YA2-M analog :R=H