| 摘要 |
A transdermal therapeutic system of the matrix type, comprising an active substance-impermeable backing layer, a detachable protective layer and an active substance-containing matrix based on hydrophobic polymers, the active substance having a melting point above room temperature and being present at least during part of the application time of the TTS in a concentration exceeding the saturation solubility, is characterized in that a polyacrylate polymer is admixed to the hydrophobic base polymers of the active substance matrix, or/and in that the matrix layer containing the hydrophobic polymers is provided with a self-adhesive skin-contact layer based on polyacrylates. |
