| 发明名称 |
Glycoconjugates from modified camptothecin derivatives (20-O-linkage) |
| 摘要 |
The present invention relates to glycoconjugates of camptothecin derivatives in which at least one carbohydrate component is linked via suitable spacers with the 20-hydroxyl group of a camptothecin derivative. The invention furthermore relates to processes for preparing the compounds according to the invention and to their use as medicaments, in particular in connection with cancer.
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| 申请公布号 |
US6492335(B1) |
申请公布日期 |
2002.12.10 |
| 申请号 |
US19990269317 |
申请日期 |
1999.03.24 |
| 申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
LERCHEN HANS-GEORG;VON DEM BRUCH KARSTEN;BUAMGARTEN JOERG;SPERZEL MICHAEL |
| 分类号 |
A61K38/00;A61P35/00;C07D491/22;C07H15/20;C07H15/26;C07K5/06;C07K5/068;C07K5/078;(IPC1-7):A61K31/70;A61K31/675;A61K31/44;C07F9/06 |
主分类号 |
A61K38/00 |
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