发明名称 |
D-ENANTIOMER OF DFMO AND METHODS OF USE THEREFOR FOR TREATING CANCER |
摘要 |
The present invention concerns a method for preventing and/or treating cancer in a patient comprising administering an effective amount of substantially purified D enantiomer of difluoromethylornithine (D-DFMO) or an analog of D-DFMO to the patient. D-DFMO or an analog thereof is administered at a dose of about 0.05 to about 20.0 gm/M2/day. D-DFMO or an analog thereof may be administered more than once for the treatment and/or prevention of cancer. Methods of administration as well as compositions and formulations of substantially purified D-DFMO and analogs of D-DFMO are described. |
申请公布号 |
EP1261326(A1) |
申请公布日期 |
2002.12.04 |
申请号 |
EP20010914781 |
申请日期 |
2001.03.07 |
申请人 |
ILEX ONCOLOGY, INC. |
发明人 |
LEVENSON, COREY;SHAKED, ZE'EV |
分类号 |
A61K9/02;A61K9/06;A61K9/08;A61K9/10;A61K9/14;A61K9/20;A61K9/48;A61K31/00;A61K31/195;A61K31/198;A61P35/00;A61P43/00 |
主分类号 |
A61K9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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