METHODS OF SYNTHESIZING ACYLANILIDES INCLUDING BICALUTAMIDE AND DERIVATIVES THEREOF
摘要
Methods of synthesizing an acylanilide include contacting a compound having the structure of Formula I with a compound having the structure of Formula II under conditions sufficient to provide a compound having the structure of Formula III and treating the compound of Formula III under conditions sufficient to provide an acylanilide. The compound of Formula III may be addition reacted with a compound having the structure of Formula IV: under conditions sufficient to provide an acylanilide having the structure of Formula V.
申请公布号
WO02088070(A1)
申请公布日期
2002.11.07
申请号
WO2002US13591
申请日期
2002.05.02
申请人
NOBEX CORPORATION;EKWURIBE, NNOCHIRI, N.;JAMES, KENNETH, D.