发明名称 |
Trockenes analytisches Element für Acetaminophenassay |
摘要 |
A spectrophotometric assay for the detection of acetaminophen in aqueous fluids is carried out with a dry analytical element. The element comprises a support having thereon one or more reagent layers containing a first enzyme, aryl acylamidase, to cleave the amide bond of acetaminophen to produce p-aminophenol; and a mild oxidizing agent to oxidize the p-aminophenol so that it couples to a water-soluble coupling agent to form a dye that is read at 670 nm. The assay is precise, accurate on serum and plasma samples, and relatively free from significant interferences. The element also allows measurement over a broad dynamic range. |
申请公布号 |
DE69620825(T2) |
申请公布日期 |
2002.10.10 |
申请号 |
DE1996620825T |
申请日期 |
1996.06.21 |
申请人 |
JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. |
发明人 |
ARTER, THOMAS C.;MAUCK, JOHN C.;SCHAEFFER, JAMES R.;WINTERKORN, ROBERT F. |
分类号 |
C12Q1/26;C12Q1/34;G01N33/52;(IPC1-7):G01N33/52 |
主分类号 |
C12Q1/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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