MEDICATED TATTOOS

摘要

A transdermal medicament delivery device in the form of a printed temporary tattoo (2) which conceals the fact that the wearer is taking a drug. The ornamental appearance actually provides an incentive for wear. The medicated tattoo (2) includes a section of cardstock base paper (70), a clear base (50 ) bearing an ink design on one side, the clear base being attached to the cardstock base paper (70) on the other side by a release base (60) that dissolves when wet to allow detachment of the base paper, and an adhesive layer (20) coated over the ink design on the clear base for adhesion to the skin. A medicament or drug (30) is incorporated into the adhesive layer for diffusion therefrom into the skin of the wearer, and the adhesive layer (20) has predetermined permeability characteristics to ensure effective transderm al delivery of the medicament (30). The process for making the transdermal tattoos includes lithographic printing and silk screen coating to create the necessary layers, inclusive of drug deposition on the control membrane. Th n et result is less susceptible to being dislodged, thereby allowing more conventional low-strength skin adhesives to make intentional removal easy an d painless. Moreover, the tattoo can provide an outward visual indication of t he progress of delivery.