发明名称 Hydroxamic acid derivatives as inhibitors of the production of human CD23 and of the TNF release
摘要 Compounds of Formula (1) wherein: R is methyl substituted by one to three groups from alkyl, aryl, alkenyl, and alkynyl; n is ) or 1; R1 is arylmethyl or heterocyclylmethyl; R2 is alkyl, alkenyl, cycloalkyl or cycloalkenyl; and R3 is hydrogen, alkyl, alkenyl, alkynyl or aryl; are useful in the treatment of disorders mediated y s-CD23.
申请公布号 US6458779(B1) 申请公布日期 2002.10.01
申请号 US20010701946 申请日期 2001.04.05
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 FALLER ANDREW;MACPHERSON DAVID TIMOTHY;MILNER PETER HENRY;MISTRY JAYSHREE;WARD JOHN GERALD
分类号 A61P29/00;A61K31/16;A61K31/165;A61K31/192;A61K31/216;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07C237/22;C07C259/06;C07C323/60;C07D207/40;C07D207/404;C07D215/14;C07D271/06;C07D277/24;C07D311/58;C07D333/54;C07D333/60;C07D521/00;(IPC1-7):A61K31/545;C07C259/04 主分类号 A61P29/00
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