发明名称 |
Non-peptide GnrH Agents, methods and intermediates for their preparation. |
摘要 |
Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, multimers, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described. |
申请公布号 |
ZA200100831(B) |
申请公布日期 |
2002.08.22 |
申请号 |
ZA20010000831 |
申请日期 |
2001.01.30 |
申请人 |
AGOURON PHARMACEUTICALS, INC. |
发明人 |
MARK BRIAN ANDERSON;HARESH N VAZIR;DAVID ROBERT LUTHIN;GENEVIEVE DEGUZMAN PADERES;VED P. PATHAK;LANCE CHRISTOPHER CHRISTIE;YUFENG HONG;EILEEN VALENZUELA TOMPKINS;HAITAO LI;JAMES FAUST |
分类号 |
C07D307/56;A61K31/34;A61K31/341;A61K31/352;A61K31/404;A61K31/4184;A61K31/427;A61K31/4375;A61K31/4427;A61K31/443;A61K31/4433;A61K31/496;A61K31/50;A61K31/501;A61K31/505;A61K31/506;A61K31/519;A61P5/02;A61P5/04;A61P13/08;A61P15/00;A61P15/16;A61P35/00;C07D307/68;C07D405/12;C07D405/14;C07D407/06;C07D409/12;C07D417/12;C07D471/04;C07D487/04 |
主分类号 |
C07D307/56 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|