| 发明名称 |
ANTISENSE MODULATION OF PROTEIN KINASE C-THETA EXPRESSION |
| 摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of Protein kinase C-theta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Protein kinase C-theta. Methods of using these compounds for modulation of Protein kinase C-theta expression and for treatment of diseases associated with expression of Protein kinase C-theta are provided.</p> |
| 申请公布号 |
EP1224203(A2) |
申请公布日期 |
2002.07.24 |
| 申请号 |
EP20000991873 |
申请日期 |
2000.10.20 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BENNETT, C., FRANK;COWSERT, LEX, M. |
| 分类号 |
C12N15/00;A61K9/107;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P3/10;A61P17/02;A61P31/18;A61P35/00;C07H19/06;C07H19/10;C07H19/16;C07H19/20;C07H21/00;C07H21/02;C12N9/99;C12N15/113;C12Q1/68;(IPC1-7):C07H21/04;C12N15/86;C12P19/34 |
主分类号 |
C12N15/00 |
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