The present invention relates to a recombinant receptor, comprising an extracellular ligand-binding domain and a cytoplasmic domain that comprises a heterologous bait polypeptide, which receptor is activated by binding of a ligand to said ligand binding domain and by binding of a prey polypeptide to said heterologous bait peptide. The present invention also relates to a method to detect compound-compound binding using said recombinant receptor.
申请公布号
WO0190188(A3)
申请公布日期
2002.06.13
申请号
WO2001EP05916
申请日期
2001.05.22
申请人
VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW;EYCKERMAN, SVEN;VAN OSTADE, XAVEER;VANDEKERCKHOVE, JOEL;VERHEE, ANNICK;TAVERNIER, JAN
发明人
EYCKERMAN, SVEN;VAN OSTADE, XAVEER;VANDEKERCKHOVE, JOEL;VERHEE, ANNICK;TAVERNIER, JAN