发明名称 CYTOTOXIC DRUG THERAPY
摘要 A compound comprises a target cell-specific portion, such as an antibody specific to tumour cell antigens, and an inactivat- ing portion, such as an enzyme, capable of converting a substance which in i ts native state is able to inhibit the effect of a cytotox- ic agent into a substance which has less effect against said cytotoxic agent . The prolonged action of a cytotoxic agent at tumour sites is therefore possible whilst protecting normal tissues from the effect s of the cytotoxic agent.
申请公布号 CA2124218(C) 申请公布日期 2002.06.11
申请号 CA19932124218 申请日期 1993.01.11
申请人 发明人 BAGSHAWE, KENNETH DAWSON
分类号 C12N15/02;A61K31/517;A61K31/519;A61K31/70;A61K31/7072;A61K38/00;A61K38/45;A61K38/46;A61K39/395;A61K45/00;A61K45/06;A61K47/48;A61K48/00;A61P35/00;A61P39/02;A61P43/00;C07H21/04;C07K14/02;C07K14/10;C07K14/18;C07K14/705;C07K16/00;C07K16/28;C07K16/30;C07K16/40;C07K16/46;C07K19/00;C12N15/09;C12P21/08;(IPC1-7):A61K47/48 主分类号 C12N15/02
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