Novel g protein-coupled receptor protein and nucleic acid molecules and uses therefor

摘要

Novel C5RL polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length C5RL proteins, the invention further provides isolated C5RL fusion proteins, antigenic peptides and anti-C5RL antibodies. The invention also provides C5RL nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a C5RL gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.