发明名称 |
Catalytic monoclonal antibodies with protease activity for selective lysis of protein component of plaques aggregates pathological conditions |
摘要 |
Catalytic monoclonal antibodies (abzymes) with selective protease activity in the pathologies characterized by the presence of plaques and fibrillar aggregates with protein component; methods for the preparation thereof and the use thereof as medicaments in the treatment of pathologies such as Alzheimer's disease, amyloidosis, atherosclerosis, prions diseases.
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申请公布号 |
US6387674(B1) |
申请公布日期 |
2002.05.14 |
申请号 |
US20000463724 |
申请日期 |
2000.02.14 |
申请人 |
ABIOGEN PHARMA S.P.A. |
发明人 |
TRASCIATTI SILVIA;ROSINI SERGIO |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P9/10;A61P25/28;A61P43/00;C07K14/47;C07K16/18;C12N5/10;C12N9/00;C12P21/08;(IPC1-7):C12N9/00 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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地址 |
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