发明名称 Catalytic monoclonal antibodies with protease activity for selective lysis of protein component of plaques aggregates pathological conditions
摘要 Catalytic monoclonal antibodies (abzymes) with selective protease activity in the pathologies characterized by the presence of plaques and fibrillar aggregates with protein component; methods for the preparation thereof and the use thereof as medicaments in the treatment of pathologies such as Alzheimer's disease, amyloidosis, atherosclerosis, prions diseases.
申请公布号 US6387674(B1) 申请公布日期 2002.05.14
申请号 US20000463724 申请日期 2000.02.14
申请人 ABIOGEN PHARMA S.P.A. 发明人 TRASCIATTI SILVIA;ROSINI SERGIO
分类号 C12N15/09;A61K38/00;A61K39/395;A61P9/10;A61P25/28;A61P43/00;C07K14/47;C07K16/18;C12N5/10;C12N9/00;C12P21/08;(IPC1-7):C12N9/00 主分类号 C12N15/09
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