| 摘要 |
The present invention provides methods for identifying an agent that alters, preferably increases, an NMDA receptor mediated response in a neuron. The method includes contacting the neuron with the agent, where the neuron includes an NMDA receptor and an elevated level of PKC. The neuron can be ex vivo, in vitro, or in vivo. The present invention also provides methods for identifying an agent that, in an animal, reduces pain from a neuropathological condition.
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