发明名称 |
Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders |
摘要 |
<p>A compound having the following general fomula: <CHEM> wherein R1 is an optionally substituted hydrocarbon, amino or heterocyclic group; R2 is H or an optionally substituted hydrocarbon group; R3 is H or an optionally substituted hydrocarbon or heterocyclic group; X is CHR4, NR4, O or S in which R4 is H or an optionally substituted hydrocarbon group; R5 is H, a halogen atom, C1-6 alkyl group, a C1-6 alkoxy group, a hydroxy group, a nitro group, a cyano group or an amino group wherein the C1-6 alkyl group, the C1-6 alkoxy group and the amino group may be substituted by 1 to 5 substituents, Y is C or N; ring B is an optionally substituted benzene ring; m = 1 to 4 and n = 0 to 2; L represents a leaving group such as a halogen atom, an alkylsulfonyl group, an alkylsulfonlyoxy group and arylsulfonyloxy group; or a salt thereof.</p> |
申请公布号 |
EP1199304(A1) |
申请公布日期 |
2002.04.24 |
申请号 |
EP20010119552 |
申请日期 |
1997.03.05 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
OHKAWA, SHIGENORI;UCHIKAWA, OSAMU;FUKATSU, KOHJI;MIYAMOTO, MASAOMI |
分类号 |
A61K31/352;A61K31/16;A61K31/335;A61K31/343;A61K31/381;A61K31/407;A61K31/4162;A61K31/4188;A61K31/424;A61K31/429;A61K45/06;C07D263/52;C07D265/34;C07D307/93;C07D311/94;C07D319/08;C07D491/04;(IPC1-7):C07D209/08;A61K31/425;A61K31/42;A61K31/415;A61K31/40;A61K31/38;A61K31/35;A61K31/34;C07D313/06;C07D311/78;C07C13/465;C07D235/06;C07D235/02;C07D333/54;C07D333/50;C07D307/79;C07D307/77;C07D277/64;C07D277/62;C07D277/60;C07D263/56;C07D209/56;C07D209/10 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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