发明名称 |
Use of a nucleic acid/pei complex |
摘要 |
The invention concerns the use of a nucleic acid/cationic polymer complex, preferably polyethyleneimine (PEI) for preparing a composition for intraventricular stereotactic screening of stem cells of the brain for preparing a medicine for treating neurodegenerative and/or demyelinating disease. The invention further concerns a method for obtaining an animal whereof the genome of stem cells of the brain are modified by using said complex. The invention also concerns a method for obtaining an animal for screening compounds designed to modify the disposition of stem cells of the brain. |
申请公布号 |
AU9197501(A) |
申请公布日期 |
2002.04.02 |
申请号 |
AU20010091975 |
申请日期 |
2001.09.21 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
BARBARA DEMENEIX;GREGORY LEMKINE;GIOVANNI LEVI |
分类号 |
A61K47/48;A61K48/00;A61P25/00;C12N15/87 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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