| 发明名称 |
Trans olefinic glucokinase activators |
| 摘要 |
2,3-Di-substituted trans olefinic N-heteroaromatic or urido propionamides with said substitution at the 2-position being a substituted phenyl group and at the 3-position being a cycloalkyl ring, said propionamides being glucokinase activators which increase insulin secretion in the treatment of type II diabetes.
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| 申请公布号 |
US6353111(B1) |
申请公布日期 |
2002.03.05 |
| 申请号 |
US20000727624 |
申请日期 |
2000.12.01 |
| 申请人 |
HOFFMANN-LA ROCHE INC. |
发明人 |
CORBETT WENDY LEA;SARABU RAMAKANTH;SIDDURI ACHYUTHARAO |
| 分类号 |
C07D277/20;A61K31/17;A61K31/426;A61K31/44;A61K31/4402;A61P3/10;A61P43/00;C07C275/48;C07C275/50;C07C317/44;C07D213/75;C07D277/44;C07D277/46;C07D277/56;(IPC1-7):C07D277/44;C07C271/00 |
主分类号 |
C07D277/20 |
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