发明名称 USE OF ANTIBODIES AGAINST SPECIFIC MHC-PEPTIDE COMPLEXES
摘要 The invention describes a method to diagnose the autoimmune disease activity by detecting the presence of an autoimmune specific MHC-peptide complex in a patient suffering from an autoimmune disease. The MHC-peptide complex is associated with rheumatoid arthritis. Monoclonals antibodies to be used for this method are also described. The antibodies can also be used for therapeutic purposes.
申请公布号 WO0214870(A2) 申请公布日期 2002.02.21
申请号 WO2001EP09136 申请日期 2001.08.08
申请人 AKZO NOBEL N.V.;STEENBAKKERS, PETRUS, GERARDUS, ANTONIUS 发明人 STEENBAKKERS, PETRUS, GERARDUS, ANTONIUS
分类号 G01N33/53;A61K39/395;A61K45/00;A61P19/02;A61P29/00;A61P37/06;C07K14/47;C07K16/18;C07K16/28;G01N33/564;G01N33/569;G01N33/68 主分类号 G01N33/53
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